The report “Definitions of CMV infection and disease in transplant patients for use in clinical trials” is now available for advance access online in Clinical Infectious Diseases (http://cid.oxfordjournals.org/content/early/2016/09/27/cid.ciw668.abstract)
During the last two decades, major advances have been made regarding the diagnosis and management of CMV in transplant patients. These advances have been made possible through the development of new diagnostic techniques for the detection of the virus and through the performance of prospective clinical trials that evaluated the efficacy and safety of novel antiviral agents. The aim of this report from the “CMV Drug Development Forum” (http://www.hivforum.org/projects/drugdevelopment/cmv) is to update the published definitions of CMV infection and disease, taking into account the current state of knowledge in this field recognizing that more work needs to be done to standardize CMV DNA quantification across laboratories and centers.
During the last two decades, major advances have been made regarding the diagnosis and management of CMV in transplant patients. These advances have been made possible through the development of new diagnostic techniques for the detection of the virus and through the performance of prospective clinical trials that evaluated the efficacy and safety of novel antiviral agents. The aim of this report from the “CMV Drug Development Forum” (http://www.hivforum.org/projects/drugdevelopment/cmv) is to update the published definitions of CMV infection and disease, taking into account the current state of knowledge in this field recognizing that more work needs to be done to standardize CMV DNA quantification across laboratories and centers.