Materials and Links"Monitoring of Long-Term Toxicities of HIV Treatments: An International Perspective" - published in AIDS 2003, 17:2407-2417 |
Background:
The expanded use of antiretroviral medications has brought to light a broad range of expected and unexpected side effects with treatment-limiting potential. The early capture of adverse events and appropriate follow-up actions and recommendations are key to rational use of antiretroviral therapies, improvement in design of treatment strategies and future drug development.
Objectives:
The Forum will bring together international experts in the fiels of pharmacoepidemiology, antiretroviral treatment, and toxicities and health resource utilization from academia, government agencies, the pharmaceutical industry, and the treatment and patient communities with the goal to:
- Catalog and assess the strengths and weaknesses of the existing mechanisms for capturing adverse events, identifying the gaps in the current surveillance activities;
- Develop recommendations for improvements in current surveillance systems and/or the design of new systems (signal detection);
- Discuss the requirements for a successful international, continuous and long-term oversight of this process and make recommendations for how to set this up; and
- Develop recommendations for appropriate action to follow signal detection.
Status:
The first workshop was held on April 17 & 18, 2002; a second workshop is planned for the winter of 2002.
Scientific chairs:
Dr. Alexander Walker (USA)
Dr. Ian Weller (UK)
Project specific sponsors:
Division of AIDS, National Institutes of Health
Forum for Collaborative HIV Research
Hoffman-La Roche
