The Obesity and Fat Metabolism in HIV-infected Individuals workshop took place at the National Institutes of Health in Rockville, MD on May 22 and 23, 2018.
Materials
Presentations
Welcome and Opening Remarks
Griffin Rodgers, Director, National Institute of Diabetes and Digestive and Kidney Diseases
Catherine Godfrey, National Institute of Allergy and Infectious Diseases
Andrew Bremer, National Institute of Diabetes and Digestive and Kidney Diseases
Session I: Overview- Setting the Stage
Chair: Peter Hunt, University of California, San Franscisco
Session Overview:
- Brown vs beige fat: generalized obesity vs dysfunctional adipose tissue
- lifespan issues
Clovis Palmer, Burnet Institute
- Epigenetic link - in utero issues
Mary-Elizabeth Patti, Joslin Diabetes Center
Aaron Cypess, National Institute of Diabetes and Digestive and Kidney Diseases
Session II: It's the Virus!
Co-Chairs: Todd Brown, Johns Hopkins University
Roger Paredes, IrsiCaixa AIDS Research Institute
Session Overview:
- Relationship between HIV and its viral products and fat
Dorothy Lewis, The University of Texas Health Science Center at Houston
Steve Grinspoon, Massachusetts General Hospital
Marta Giralt, University of Barcelona
Session III: Immune and Metabolic Interactions
Co-Chairs: Steve Grinspoon, Massachusetts General Hospital
Jason Baker, University of Minnesota
Session Overview:
Suneil Koliwad, University of California San Francisco
Alyssa Hasty, Vanderbilt University School of Medicine
John Koethe, Vanderbilt University
Session IV: GI Tract and Adipocyte Interactions
Co-Chairs: Rohit Loomba, University of California, San Diego
Netanya Utay, University of Texas Houston
Session Overview:
- The interplay between HIV and the GI tract, adipose tissue, and the liver
- Other microbial "players" involved in mediating interactions between HIV and tissues
Janet Lo, Massachusetts General Hospital
- Microbiome and products of microbial metabolism
Ivan Vujkovic -Cvijin, National Institute of Allergy and Infectious Diseases
Colleen Hadigan, National Institute of Allergy and Infectious Diseases
Session V: Pharmacology and Treatment of Obesity
Chair: Jordan Lake,
University of Texas Health Science Center
Session Overview:
- Non-viral effects of current HIV therapy
- Viral and non-viral considerations for future HIV therapies
Grace McComsey, University Hospitals Health System and Case Western Reserve University
Alex Soukas, Center for Genomic Medicine
Steven Heymsfield, Pennington Biomedical Research Center
Session VI: How do we translate this information to the clinic? What clinical trials are needed? What tools are needed?
Co-Chairs: Judith Currier, University of California, Los Angeles
Grace Aldrovandi, University of California, Los Angeles
Session Overview:
- Moving the science forward
- What clinical trials are needed?
- What tools are needed?
Caroline Apovian, Boston University School of Medicine
Turner Overton, University of Alabama School of Medicine
This workshop was sponsored by:
National Institute of Allergy and Infectious Diseases
National Institute of Diabetes and Digestive and Kidney Diseases
National Institues of Health Office of AIDS Research
National Instiutes of Health Office of Research on Women's Health